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Three-dimensional numerical simulation of flow in trapezoidal cutthroat flumes based on FLOW-3D

Danjie RAN, Wene WANG, Xiaotao HU

《农业科学与工程前沿（英文）》 2018年第5卷第2期页码 168-176 doi: 10.15302/J-FASE-2018217

摘要： To solve the common problem of flumes flow-measurement accuracy without sacrificing water head, a new type of trapezoidal cutthroat flume to measure the discharge in terminal trapezoidal channels is presented. Using the computational fluid dynamic method, three-dimensional flow fields in trapezoidal cutthroat flumes were simulated using the RNG three-dimensional turbulence model along with the TruVOF technique. Simulations were performed for 12 working conditions, with discharges up to 0.075 m ·s to determine hydraulic performance. Experimental data for the trapezoidal cutthroat flume in terminal trapezoidal channel were also obtained to validate the simulation results. Velocity distribution of the flume obtained from simulation analyses were compared with observed results based on time-averaged flow field and comparison yielded a solid agreement between results from the two methods, with relative error below 10%. The results indicated that the Froude number and the longitudinal average velocity increased along the convergence section and decreased in the divergent section. In the upper throat, the Froude number was less than 0.5, which meets the water measurement requirement, and the critical flow appeared near the throat section. The maximum water head loss of the trapezoidal cutthroat flume was less than 9% of the total head, compared to the rectangular cutthroat flume, and head loss of trapezoidal cutthroat flume was significantly less. Regression models developed for upstream depth versus discharge under different working conditions were satisfactory, with a relative error of less than 2.06%, which meets the common requirements of flow measurement in irrigation areas. It was concluded that trapezoidal cutthroat flumes can improve flow-measurement accuracy without sacrificing water head.

关键词： distribution of velocity Froude number head loss stage-discharge relationship trapezoidal cutthroat flume

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搅拌摩擦焊镁合金隔声性能的研究

刘成武,钱林方

《中国工程科学》 2014年第16卷第8期页码 93-98

摘要：

伴随搅拌摩擦焊在镁合金上的广泛应用，对其隔声特性研究尤为重要，基于自适应网格技术，对搅拌摩擦焊过程进行数值模拟，为后续声学计算提供约束模态，解决了材料属性难以确定的问题，一定程度上实现了焊接与声学的结合。自行设计和制造了混响箱，用以测量焊接镁合金板的隔声量，弥补了混响室测试小试件的不足。进而使用finite element-statistical energy analysis（FE-SEA）混合法计算焊接件的隔声量，与试验结果进行对比，吻合良好，表明此方法行之有效。通过对比焊接前后镁合金板件的隔声量，发现在吻合低谷区，焊接后板件的隔声有所降低。为了研究焊接参数对隔声的影响，分别改变焊接速度和搅拌头旋转速度，观察隔声量的变化，结果表明，这些参数都需要合理的设置，并非越大或者越小越好。

关键词：搅拌摩擦焊混响箱 FE-SEA混合法焊接速度搅拌头旋转速度

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Expression pattern and regulation of head-to-head genes

Xinxing CUI,Chunhong YANG,Li KANG,Guiyu ZHU,Qingqing WEI,Yunliang JIANG

《农业科学与工程前沿（英文）》 2014年第1卷第2期页码 130-136 doi: 10.15302/J-FASE-2014013

摘要： Vacuolar protein sorting 36 (VPS36), a protein primarily known for its role in the Endosomal Sorting Complex Required for Transport pathway, has recently been shown to be linked to chicken reproduction. Previous research showed that is significantly downregulated in sexually mature chicken ovaries compared to immature ones. In this study, using real-time quantitative RT-PCR, we investigated the expression pattern of and its head-to-head gene mRNA in chicken follicles. Small white follicles were found to have significantly higher expression of and mRNA than any other sized follicles ( <0.05). The expression of and mRNA were detected in both granulosa and theca layers of pre-ovulatory follicles, the expression of in theca layers was slightly higher than in granulosa cells. Treatment of small yellow follicles with follicle-stimulating hormone and estradiol resulted in a marked decrease of both and mRNA ( <0.05); however, progesterone, transforming growth factor-β 1 and luteinizing hormone induced no significant changes in and mRNA expression in these follicles. These results indicate that the head-to-head genes of and exhibit similar expression in chicken follicles and are involved in chicken follicle development.

关键词： chicken Vps36 Ckap2 mRNA follicle

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Basic consideration of research strategies for head and neck cancer

null

《医学前沿（英文）》 2012年第6卷第4期页码 339-353 doi: 10.1007/s11684-012-0213-7

摘要：

Head and neck cancer (HNC) consists of a group of malignancies affecting closely related anatomical regions of the upper aerodigestive tract (UADT), including the oral cavity, salivary glands, upper and lower jaw bones and facial skin; the nasal cavity, paranasal sinuses, pharynx, larynx and thyroid gland (although the latter is often excluded and considered as part of endocrine neoplasms). Of these, 90% of HNCs are histologically squamous cell carcinomas originating from the mucosal lining. These malignancies are strongly associated with certain environmental and life-style risk factors, principally tobacco in both smoked and smokeless forms, excessive alcohol consumption, diets poor in antioxidants and essential micronutrients, UV light, chemicals used in certain workplaces, and viruses, principally certain strains of human papillomavirus (HPV) and Epstein-Barr virus (EBV). These cancers are frequently aggressive in their biological behaviour with local invasion and metastasis to lymph nodes in the neck. Since most patients are already at late stages of disease at the time of diagnosis, the desirable practice of early diagnosis (first sign of the malignant lesion at an initial stage ) and early treatment, a critical priority to save lives and retain quality of life, is difficult to implement. Thus, primary prevention has been set as a key goal. This article aims to reinforce the basic knowledge of aetiology, key risk factors related to the development of head and neck cancer, basic features of clinical appearance of this group of cancers, and strategies for prevention and early detection. We also suggest basic research strategies on the basis of current knowledge, which should ultimately lead to the improvement of clinical management.

关键词： clinical management head and neck cancer prevention and early detection research strategies risk factors

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Influence of surface cracking, anchor head profile, and anchor head size on cast-in headed anchors in

《结构与土木工程前沿（英文）》页码 1163-1187 doi: 10.1007/s11709-023-0987-5

摘要： In this study, the concrete cone capacity, concrete cone angle, and load–displacement response of cast-in headed anchors in geopolymer concrete are explored using numerical analyses. The concrete damaged plasticity (CDP) model in ABAQUS is used to simulate the behavior of concrete substrates. The tensile behavior of anchors in geopolymer concrete is compared with that in normal concrete as well as that predicted by the linear fracture mechanics (LFM) and concrete capacity design (CCD) models. The results show that the capacity of the anchors in geopolymer concrete is 30%–40% lower than that in normal concrete. The results also indicate that the CCD model overestimates the capacity of the anchors in geopolymer concrete, whereas the LFM model provides a much more conservative prediction. The extent of the difference between the predictions by the numerical analysis and those of the above prediction models depends on the effective embedment depth of the anchor and the anchor head size. The influence of concrete surface cracking on the capacity of the anchor is shown to depend on the location of the crack and the effective embedment depth. The influence of the anchor head profile on the tensile capacity of the anchors is found to be insignificant.

关键词： cast-in anchor concrete cone capacity geopolymer concrete head size surface crack anchor profile

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factors for ventilator-associated pneumonia among patients undergoing major oncological surgery for head

null

《医学前沿（英文）》 2017年第11卷第2期页码 239-246 doi: 10.1007/s11684-017-0509-8

摘要：

Patients undergoing major oncological surgery for head and neck cancer (SHNC) have a particularly high risk of nosocomial infections. We aimed to identify risk factors for ventilator-associated pneumonia (VAP) in patients undergoing SHNC. The study included 465 patients who underwent SHNC between June 2011 and June 2014. The rate of VAP, risk factors for VAP, and biological aspects of VAP were retrospectively evaluated. The incidence of VAP was 19.6% (n=95) in patients who required more than 48 h of mechanical ventilation. Staphylococcus (37.7%), Enterobacteriaceae (32.1%), Pseudomonas(20.8%), and Haemophilus (16.9%) were the major bacterial species that caused VAP. The independent risk factors for VAP were advanced age, current smoking status, chronic obstructive pulmonary disease, and a higher simplified acute physiology score system II upon admission. Tracheostomy was an independent protective factor for VAP. The median length of stay in the ICU for patients who did or did not develop VAP was 8.0 and 6.5 days, respectively (P=0.006). Mortality among patients who did or did not develop VAP was 16.8% and 8.4%, respectively (P<0.001). The potential economic impact of VAP was high because of the significantly extended duration of ventilation. A predictive regression model was developed with a sensitivity of 95.3% and a specificity of 69.4%. VAP is common in patients who are undergoing SHNC and who require more than 48 h of mechanical ventilation. Therefore, innovative preventive measures should be developed and applied in this high-risk population.

关键词： ventilator-associated pneumonia (VAP) pneumonia risk factors surgery for head and neck cancer (SHNC)

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Model test study for ice force on the bank-head of the lead-navigating bank

SONG An, SUN Jinliang, LU Hai, WANG Yi′an

《结构与土木工程前沿（英文）》 2007年第1卷第2期页码 222-228 doi: 10.1007/s11709-007-0027-x

摘要： To determine the bank-head s ice force of the lead-navigating bank at key position that faces the ice directly of certain water conservancy, ice model test in reduced scale is designed and carried out based on the local situation on the spot and data observed. Preliminary conclusions are got through the analysis of the experimental data such as effect of the ice velocity on the ice force , ratio of components of forces when ice sheet acting on the vertical bank-head, ice force ratio of vertical to 45? incline as well as ratio of level ice force to the vertical ice force when acting on 45? incline. Finally, suggestions on determination of the ice force using formula are given after comparison between the result calculated by the present formula of ice force and the experimental results.

关键词： comparison lead-navigating bank vertical bank-head certain Preliminary

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Panoramic variation analysis of a family with neurodevelopmental disorders caused by biallelic loss-of-function

《医学前沿（英文）》 doi: 10.1007/s11684-023-1006-x

摘要： Highly clinical and genetic heterogeneity of neurodevelopmental disorders presents a major challenge in clinical genetics and medicine. Panoramic variation analysis is imperative to analyze the disease phenotypes resulting from multilocus genomic variation. Here, a Pakistani family with parental consanguinity was presented, characterized with severe intellectual disability (ID), spastic paraplegia, and deafness. Homozygosity mapping, integrated single nucleotide polymorphism (SNP) array, whole-exome sequencing, and whole-genome sequencing were performed, and homozygous variants in TMEM141 (c.270G>A, p.Trp90*), DDHD2 (c.411+767_c.1249-327del), and LHFPL5 (c.250delC, p.Leu84*) were identified. A Tmem141^{p.Trp90*/p.Trp90*} mouse model was generated. Behavioral studies showed impairments in learning ability and motor coordination. Brain slice electrophysiology and Golgi staining demonstrated deficient synaptic plasticity in hippocampal neurons and abnormal dendritic branching in cerebellar Purkinje cells. Transmission electron microscopy showed abnormal mitochondrial morphology. Furthermore, studies on a human in vitro neuronal model (SH-SY5Y cells) with stable shRNA-mediated knockdown of TMEM141 showed deleterious effect on bioenergetic function, possibly explaining the pathogenesis of replicated phenotypes in the cross-species mouse model. Conclusively, panoramic variation analysis revealed that multilocus genomic variations of TMEM141, DDHD2, and LHFPL5 together caused variable phenotypes in patient. Notably, the biallelic loss-of-function variants of TMEM141 were responsible for syndromic ID.

关键词： neurodevelopmental disorder autosomal recessive intellectual disability consanguinity spastic paraplegia hearing loss TMEM141

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Biologically inspired model of path integration based on head direction cells and grid cells

Yang ZHOU,De-wei WU

《信息与电子工程前沿（英文）》 2016年第17卷第5期页码 435-448 doi: 10.1631/FITEE.1500364

摘要： Some neurons in the brain of freely moving rodents show special firing pattern. The firing of head direction cells (HDCs) and grid cells (GCs) is related to the moving direction and distance, respectively. Thus, it is considered that these cells play an important role in the rodents’ path integration. To provide a bionic approach for the vehicle to achieve path integration, we present a biologically inspired model of path integration based on the firing characteristics of HDCs and GCs. The detailed implementation process of this model is discussed. Besides, the proposed model is realized by simulation, and the path integration performance is analyzed under different conditions. Simulations validate that the proposed model is effective and stable.

关键词： Head direction cells (HDCs) Grid cells (GCs) Path integration Bionic navigation

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Ultramicrostructure and clinical implications of satellite foci in front of the head of pterygium

LIU Haixia, XIANG Nan, ZHOU Xiongwu, HU Weikun, LI Guigang, ZHANG Hong

《医学前沿（英文）》 2007年第1卷第2期页码 211-214 doi: 10.1007/s11684-007-0040-4

摘要： In our previous studies, grey satellite foci were found in the front of heads of pterygia. This research was designed to investigate the ultramicrostructure and clinical implications of these satellite foci. The satellite foci were observed and counted under slit lamp biomicroscope. The patients with eye pterygia were divided into groups in terms of occupation, sex, age, length of history, grade of congestion, and size of the heads. The SPSS 13.0 software was used for statistical analysis. The cap areas and satellite foci were ultramicrostructurally examined. Among the total 62 eyes with pterygium, satellite foci were found in 34. The overall incidence of satellite foci was 54.8%. There were no significant differences in incidence among the subjects of different sex, age, and length of history. There were significant differences in incidence among the patients of different occupation, grades of congestion, and size of heads. Higher grades of congestion, outdoor occupations and larger pterygium heads were associated with higher incidence of satellite foci. High grades of congestion and bigger heads were also correlated with the number of satellite foci. Length of history bore no correlation with number of satellite foci. Histologically, the components of the cap areas and the foci were identical, with both consisting of mass of active fibroblasts. The activated fibroblasts existed in the natural tissue planes between Bowman s layer and basal cell layer. The fibroblasts in the satellite foci and the cap areas of a pterygium show some features of tumor cells and may play a vital role in the development and progression of a pterygium. The presence and amount of satellite foci around a pterygium can be used as an indicator for the speed of its growth.

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Power fluctuation and power loss of wind turbines due to wind shear and tower shadow

Binrong WEN, Sha WEI, Kexiang WEI, Wenxian YANG, Zhike PENG, Fulei CHU

《机械工程前沿（英文）》 2017年第12卷第3期页码 321-332 doi: 10.1007/s11465-017-0434-1

摘要：

The magnitude and stability of power output are two key indices of wind turbines. This study investigates the effects of wind shear and tower shadow on power output in terms of power fluctuation and power loss to estimate the capacity and quality of the power generated by a wind turbine. First, wind speed models, particularly the wind shear model and the tower shadow model, are described in detail. The widely accepted tower shadow model is modified in view of the cone-shaped towers of modern large-scale wind turbines. Power fluctuation and power loss due to wind shear and tower shadow are analyzed by performing theoretical calculations and case analysis within the framework of a modified version of blade element momentum theory. Results indicate that power fluctuation is mainly caused by tower shadow, whereas power loss is primarily induced by wind shear. Under steady wind conditions, power loss can be divided into wind farm loss and rotor loss. Wind farm loss is constant at 3α(3α−1)R²/(8H²). By contrast, rotor loss is strongly influenced by the wind turbine control strategies and wind speed. That is, when the wind speed is measured in a region where a variable-speed controller works, the rotor loss stabilizes around zero, but when the wind speed is measured in a region where the blade pitch controller works, the rotor loss increases as the wind speed intensifies. The results of this study can serve as a reference for accurate power estimation and strategy development to mitigate the fluctuations in aerodynamic loads and power output due to wind shear and tower shadow.

关键词： wind turbine wind shear tower shadow power fluctuation power loss

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Turnover and loss of nitrogenous compounds during composting of food wastes

YANG Yanmei, ZHANG Xiangfeng, YANG Zhifeng, XI Beidou, LIU Hongliang

《环境科学与工程前沿（英文）》 2008年第2卷第2期页码 251-256 doi: 10.1007/s11783-008-0042-8

摘要： Few people have so far explored into the research of the dynamics of various nitrogenous compounds (including water-soluble nitrogen) in composting of food wastes. This study aimed to investigate the solid-phase nitrogen, water-soluble nitrogen, nitrogen loss together with ammonia volatilization in the process of food wastes composting. A laboratory scale static aerobic reactor in the experiment was employed in the composting process of a synthetic food waste, in which sawdust was used as the litter amendment. In the experiment, oxygen was supplied by continuous forced ventilation for 15 days. The results have shown that the concentrations of total nitrogen and organic nitrogen decrease significantly in the composting process, whereas NH-N concentration increases together with little fluctuation in NO-N. After composting, the total content of the water-soluble nitrogen compounds in the compost greatly increased, the total nitrogen loss amounted to 50% of the initial nitrogen, mainly attributed to ammonia volatilization. 56.7% of the total ammonia volatilization occurred in the middle and late composting of the thermophilic stage. This suggested that the control at the middle and late composting of thermophilic stage is the key to nitrogen loss in the food waste compost.

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Winner determination problem with loss-averse buyers in reverse auctions

Xiaohu QIAN, Min HUANG, Yangyang YU, Xingwei WANG

《工程管理前沿（英文）》 2017年第4卷第2期页码 212-220 doi: 10.15302/J-FEM-2017019

摘要： Reverse auctions have been widely adopted for purchasing goods and services. This paper considers a novel winner determination problem in a multiple-object reverse auction in which the buyer involves loss-averse behavior due to uncertain attributes. A corresponding winner determination model based on cumulative prospect theory is proposed. Due to the NP-hard characteristic, a loaded route strategy is proposed to ensure the feasibility of the model. Then, an improved ant colony algorithm that consists of a dynamic transition strategy and a Max-Min pheromone strategy is designed. Numerical experiments are conducted to illustrate the effectiveness of the proposed model and algorithm. We find that under the loaded route strategy, the improved ant colony algorithm performs better than the basic ant colony algorithm. In addition, the proposed model can effectively characterize the buyer’s loss-averse behavior.

关键词： reverse auction loss aversion winner determination improved ant colony algorithm

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A novel energy loss model and optimization design of the coin chute flection curve

Qinghua LIANG, Jinqiu MO, Weizhong GUO

《机械工程前沿（英文）》 2012年第7卷第1期页码 38-46 doi: 10.1007/s11465-012-0311-x

摘要：

In this paper, we propose a novel design model based on the energy loss of the coin (ELM model) to optimize the flection curve, which is widely used in coin operated machines. Two different kinds of energy loss models are analyzed according to dynamic characteristics of the coin falling movement. The flection curve is constructed based on cubic quasi-uniform B-spline with the data points and end points derivatives as inputs, and the curve model is governed and affected by energy loss equations, allowing to minimize the total energy loss before the coin arrives at the detecting position, thus to reduce the energy loss and collisions between the coin and the flection, thus to improve the testing accuracy. A case study with a typical Chinese currency coin shows the effectiveness of the model using GA optimization toolbox.

关键词： flection curve B-spline energy loss model (ELM model) optimization design

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Power system reconfiguration and loss minimization for a distribution systems using “Catfish PSO” algorithm

K Sathish KUMAR,S NAVEEN

《能源前沿（英文）》 2014年第8卷第4期页码 434-442 doi: 10.1007/s11708-014-0313-y

摘要： One of the very important ways to save electrical energy in the distribution system is network reconfiguration for loss reduction. Distribution networks are built as interconnected mesh networks; however, they are arranged to be radial in operation. The distribution feeder reconfiguration is to find a radial operating structure that optimizes network performance while satisfying operating constraints. The change in network configuration is performed by opening sectionalizing (normally closed) and closing tie (normally opened) switches of the network. These switches are changed in such a way that the radial structure of networks is maintained, all of the loads are energized, power loss is reduced, power quality is enhanced, and system security is increased. Distribution feeder reconfiguration is a complex nonlinear combinatorial problem since the status of the switches is non-differentiable. This paper proposes a new evolutionary algorithm (EA) for solving the distribution feeder reconfiguration (DFR) problem for a 33-bus and a 16-bus sample network, which effectively ensures the loss minimization.

关键词： distribution system reconfiguration (DFR) power loss reduction catfish particle swarm optimization (catfish PSO) radial structure